The aim of this study is to determine the relationship and predictive contribution of sense of meaning in life and sense of coherence in post-traumatic growth in recovered married people from COVID-19  in Ilam. The design of the present study was quantitative, cross-sectional and correlational, in which the relationship and prediction of the dependent variable (post-traumatic growth) was determined based on independent variables (sense of meaning in life and sense of cohesion). The statistical population of the present study included all patients with coronary heart disease (5000 people) in Ilam city who were discharged from Mostafa Khomeini Hospital in Region 4 (Ilam). The sample of this study was determined based on the number of statistical population; in this way, first the population size was determined and then according to Morgan table, the sample size (350 people) was calculated  and 198  were male and 152 were female. The sampling method was random. Data were collected based on the Meaning of Life Questionnaire by Estger and Oishi (2004), the Antonovsky Coherence Questionnaire (1993) and the Tedeschi Vacalon Post-Traumatic Development Questionnaire (1996). The results showed that the sense of meaning in life and the sense of cohesion significantly predict post-traumatic growth. This means that the higher the sense of meaning in life and the sense of cohesion in those who have recovered from COVID-19, the more post-traumatic growth they experienced (p <0.05). Based on these results, it can be said that strengthening the sense of meaning in life and the sense of cohesion in people with coronavirus can be considered as an important item for the possibility of tolerating this disease, as well as changes and positive growth after it.